Editing Liver function tests (section)

===Alpha-fetoprotein===
{| class="wikitable" align="right"
| Reference range
|-
|0-15 μg/L<ref name="Shivaraj 2009"/>
|}
{{Main|Alpha-fetoprotein}}
Alpha-fetoprotein (AFP) is significantly expressed in foetal liver. However, the mechanism that led to the suppression of AFP synthesis in adults is not fully known. Exposure of the liver to cancer-causing agents and arrest of liver maturation in childhood can lead to the rise in AFP. AFP can reach until 400–500 μg/L in [[hepatocellular carcinoma]]. AFP concentration of more than 400 μg/L is associated with greater tumour size, involvement of both lobes of liver, portal vein invasion and a lower median survival rate.<ref name="Shivaraj 2009"/>