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Triptan
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===Pharmacokinetics=== Triptans have a wide variety of [[pharmacokinetic]] properties. [[Bioavailability]] is between 14% and 70%, [[biological half-life]] (T<sub>1/2</sub>) is between 2 and 26 hours. Their good ability to cross the [[blood–brain barrier]] and the rather long half life of some triptans may result in lower frequencies of migraine recurrence.<ref name="Goodman" /><ref name="Bigal">{{cite journal | last1 = Bigal | first1 = M. E. | last2 = Bordini | first2 = C. A. | last3 = Antoniazzi | first3 = A. L. | last4 = Speciali | first4 = J. G. | year = 2003 | title = The triptan formulations: a critical evaluation | journal = Arquivos de Neuro-Psiquiatria | volume = 61 | issue = 2A | pages = 313–320 | doi = 10.1590/s0004-282x2003000200032 | pmid = 12806521 | doi-access = free }}</ref><ref name="Armstrong">{{cite journal | last1 = Armstrong | first1 = S. C. | last2 = Cozza | first2 = K. L. | year = 2002 | title = Triptans | journal = Psychosomatics | volume = 43 | issue = 6| pages = 502–504 | doi = 10.1176/appi.psy.43.6.502 | pmid=12444236| doi-access = free }}</ref><ref name="Mathew">{{cite journal | last1 = Mathew | first1 = N. T. | last2 = Loder | first2 = E. W. | year = 2005 | title = Evaluating the triptans | doi = 10.1016/j.amjmed.2005.01.017 | pmid = 15841885 | journal = The American Journal of Medicine Supplements | volume = 118 | issue = 1| pages = 28–35 }}</ref>
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