Editing Colostrum (section)

=== Hyperimmune ===
Hyperimmune colostrum is natural bovine colostrum collected from a population of cows immunized repeatedly with a specific pathogen. The colostrum is collected within 24 hours of the cow giving birth. Antibodies towards the specific pathogens or antigens that were used in the immunization are present in higher levels than in the population before treatment. Although some papers have been published stating that specific human pathogens were just as high as in hyperimmune colostrum, and natural colostrum nearly always had higher antibody titers than did the hyperimmune version.<ref name="McConnell2001"/> A clinical trial<ref>{{cite journal | vauthors = Otto W, Najnigier B, Stelmasiak T, Robins-Browne RM | title = Randomized control trials using a tablet formulation of hyperimmune bovine colostrum to prevent diarrhea caused by enterotoxigenic Escherichia coli in volunteers | journal = Scandinavian Journal of Gastroenterology | volume = 46 | issue = 7–8 | pages = 862–868 | date = July 2011 | pmid = 21526980 | pmc = 3154584 | doi = 10.3109/00365521.2011.574726 }}</ref> showed that if the immunization is by surface antigens of a strain of E. coli bacteria, the Bovine Colostrum Powder <ref>TGA guidance BCP</ref> can be used to make tablets capable of binding to the bacteria so that they are excreted in stools, thus preventing diarrhea that is caused by this strain of E. coli. This prevents the successful colonization of the gut, which would otherwise lead to bacteria releasing enterotoxigenic materials which cause diarrhea.