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Multiple sclerosis
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===Impact of temperature=== MS symptoms may increase if body temperature is dysregulated.<ref name="Heat and cold sensitivity in multiple sclerosis">{{Cite journal|url=https://www.msard-journal.com/article/S2211-0348(22)00583-1/fulltext|title=Heat and cold sensitivity in multiple sclerosis: A patient-centred perspective on triggers, symptoms, and thermal resilience practices - Multiple Sclerosis and Related Disorders|date=2022 |pmid=35963205 |access-date=15 March 2024|archive-date=15 March 2024|archive-url=https://web.archive.org/web/20240315165409/https://www.msard-journal.com/article/S2211-0348(22)00583-1/fulltext|url-status=live |journal=Multiple Sclerosis and Related Disorders |volume=67 |doi=10.1016/j.msard.2022.104075 | vauthors = Christogianni A, O'Garro J, Bibb R, Filtness A, Filingeri D }}</ref><ref name="Davis-2010">{{cite journal | vauthors = Davis SL, Wilson TE, White AT, Frohman EM | title = Thermoregulation in multiple sclerosis | journal = Journal of Applied Physiology | volume = 109 | issue = 5 | pages = 1531β1537 | date = November 2010 | pmid = 20671034 | pmc = 2980380 | doi = 10.1152/japplphysiol.00460.2010 }}</ref><ref name="Davis-2018">{{cite book | vauthors = Davis SL, Jay O, Wilson TE |chapter=Thermoregulatory dysfunction in multiple sclerosis | veditors = Romanovsky AA |title=Thermoregulation: From Basic Neuroscience to Clinical Neurology, Part II |series=Handbook of Clinical Neurology |date=2018 |volume=157 |pages=701β714 |isbn=978-0-444-64074-1 |pmid=30459034 |doi=10.1016/B978-0-444-64074-1.00042-2 }}</ref> Fatigue is particularly affected.<ref name="Multiple Sclerosis Trust"/><ref name="Christogianni-2018"/><ref name="Heat Sensitivity"/><ref name="Multiple Sclerosis Trust-2"/><ref name="Staff-2014">{{Cite web|url=https://multiplesclerosisnewstoday.com/multiple-sclerosis-news/2014/08/11/higher-body-temperature-in-rrms-patients-could-cause-increased-fatigue/|title=Higher Body Temperature in RRMS Patients Could Cause Increased Fatigue|first=BioNews|last=Staff|date=August 11, 2014|website=multiplesclerosisnewstoday.com|access-date=15 March 2024|archive-date=15 March 2024|archive-url=https://web.archive.org/web/20240315125742/https://multiplesclerosisnewstoday.com/multiple-sclerosis-news/2014/08/11/higher-body-temperature-in-rrms-patients-could-cause-increased-fatigue/|url-status=live}}</ref><ref name="Sumowski-2014">{{cite journal | vauthors = Sumowski JF, Leavitt VM | title = Body temperature is elevated and linked to fatigue in relapsing-remitting multiple sclerosis, even without heat exposure | journal = Archives of Physical Medicine and Rehabilitation | volume = 95 | issue = 7 | pages = 1298β1302 | date = July 2014 | pmid = 24561056 | pmc = 4071126 | doi = 10.1016/j.apmr.2014.02.004 }}</ref><ref>{{cite journal | vauthors = Leavitt VM, De Meo E, Riccitelli G, Rocca MA, Comi G, Filippi M, Sumowski JF | title = Elevated body temperature is linked to fatigue in an Italian sample of relapsing-remitting multiple sclerosis patients | journal = Journal of Neurology | volume = 262 | issue = 11 | pages = 2440β2442 | date = November 2015 | pmid = 26223805 | doi = 10.1007/s00415-015-7863-8 }}</ref><ref name="Christogianni-2022">{{cite journal | vauthors = Christogianni A, O'Garro J, Bibb R, Filtness A, Filingeri D | title = Heat and cold sensitivity in multiple sclerosis: A patient-centred perspective on triggers, symptoms, and thermal resilience practices | journal = Multiple Sclerosis and Related Disorders | volume = 67 | pages = 104075 | date = November 2022 | pmid = 35963205 | doi = 10.1016/j.msard.2022.104075 }}</ref>
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