Editing Pacemaker (section)

== Conduction System Pacing ==
Conventional placement of ventricular leads in or around the tip or ''apex'' of the right ventricle, or RV apical pacing, can have negative effects on heart function. It has been associated with increased risk of [[atrial fibrillation]], [[heart failure]], weakening of the heart muscle and potentially shorter life expectancy. [[bundle of his|His bundle pacing]] (HBP) and left bundle branch area pacing (LBBAP) leads to a more natural or perfectly natural ventricular activation and has generated strong research and clinical interest. By stimulating the [[Purkinje fibers|His–Purkinje]] fiber network directly with a special lead and placement technique, HBP causes a synchronized and therefore more effective ventricular activation and avoids long-term heart muscle disease. HBP in some cases can also correct [[bundle branch block]] patterns.<ref>{{cite journal |last1=Sharma |first1=Parikshit S. |last2=Vijayaraman |first2=Pugazhendhi |last3=Ellenbogen |first3=Kenneth A. |title=Permanent His bundle pacing: shaping the future of physiological ventricular pacing |journal=Nature Reviews Cardiology |volume=17 |issue=1 |pages=22–36 |doi=10.1038/s41569-019-0224-z |pmid=31249403 |year=2020 |s2cid=195698761 }}</ref><ref>{{cite journal |title=Focus on Electrophysiology: His Bundle Pacing: A More Physiologic Alternative For Pacing |journal=American College of Cardiology |date=April 26, 2019 |url=https://www.acc.org/latest-in-cardiology/articles/2019/04/14/12/42/focus-on-ep-his-bundle-pacing-a-more-physiologic-alternative-for-pacing }}</ref>