Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
Snakebite
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
=== In development === Several new drugs and treatments are under development for snakebite. For instance, the metal chelator [[dimercaprol]] has recently been shown to potently antagonize the activity of Zn<sup>2+</sup>-dependent snake venom [[metalloproteinase]]s ''in vitro''.<ref>{{cite journal | vauthors = Albulescu LO, Hale MS, Ainsworth S, Alsolaiss J, Crittenden E, Calvete JJ, Evans C, Wilkinson MC, Harrison RA, Kool J, Casewell NR | display-authors = 6 | title = Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite | journal = Science Translational Medicine | volume = 12 | issue = 542 | pages = eaay8314 | date = May 2020 | pmid = 32376771 | pmc = 7116364 | doi = 10.1126/scitranslmed.aay8314}}</ref> New [[Monoclonal antibody|monoclonal antibodies]], polymer gels and a small molecule inhibitor called [[Varespladib]] are in development.<ref>{{cite web|title=The search for better antivenoms heats up as snakebites get renewed attention|url=https://cen.acs.org/biological-chemistry/biotechnology/search-better-antivenoms-heats-snakebites/97/i4|access-date=2020-10-15|website=Chemical & Engineering News|language=en}}</ref> A core outcome set (minimal list of consensus outcomes that should be used in future intervention research) for snakebite in South Asia is being developed.<ref>{{cite journal |last1=Bhaumik |first1=Soumyadeep |last2=Beri |first2=Deepti |last3=Tyagi |first3=Jyoti |last4=Clarke |first4=Mike |last5=Sharma |first5=Sanjib Kumar |last6=Williamson |first6=Paula R. |last7=Jagnoor |first7=Jagnoor |date=2022-06-08 |title=Outcomes in intervention research on snakebite envenomation: a systematic review |journal=F1000Research |volume=11 |page=628 |doi=10.12688/f1000research.122116.1 |pmid=36300033 |pmc=9579743 |language=en |doi-access=free}}</ref>
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)