Editing Transdifferentiation (section)

===Order of transcription factor expression===

The order of expression of transcription factors can direct the fate of the cell. Iwasaki et al. (2006) showed that in hematopoietic lineages, the expression timing of [[Gata-2]] and [[(C/EBPalpha)]] can change whether or not a [[lymphoid-committed progenitor]]s can differentiate into [[granulocyte]]/[[monocyte]] progenitor, [[eosinophil]], [[basophil]] or bipotent [[basophil]]/[[mast cell]] progenitor lineages.<ref>{{Cite journal 
| last1 = Iwasaki | first1 = H. 
| last2 = Mizuno | first2 = S. -I. 
| last3 = Arinobu | first3 = Y. 
| last4 = Ozawa | first4 = H. 
| last5 = Mori | first5 = Y. 
| last6 = Shigematsu | first6 = H. 
| last7 = Takatsu | first7 = K. 
| last8 = Tenen | first8 = D. G. 
| last9 = Akashi | first9 = K. 
| doi = 10.1101/gad.1493506 
| title = The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages 
| journal = Genes & Development 
| volume = 20 
| issue = 21 
| pages = 3010–3021 
| year = 2006 
| pmid = 17079688 
| pmc =1620021 
}}</ref>