Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
World Community Grid
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
===Human Proteome Folding – Phase 1=== {{Main|Human Proteome Folding Project}} The first project launched on World Community Grid was the Human Proteome Folding Project, or HPF1, which aims to predict the structure of human [[proteins]]. The project was launched on November 16, 2004,<ref name="Completed Research" /> and completed on July 18, 2006.<ref name="Completed Research" /> This project was unique in that computation was done in tandem with the [[grid.org]] distributed computing project.<ref>{{cite web |url=http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=7683 |title=Launch of Human Proteome Folding Phase 2 project |author=Viktors |publisher=World Community Grid |date=2006-06-26 |access-date=2007-08-04 |archive-date=2019-02-04 |archive-url=https://web.archive.org/web/20190204122437/https://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=7683 |url-status=live }}</ref> Devised by Richard Bonneau at the [[Institute for Systems Biology]], the project used grid computing to produce the likely structures for each of the proteins using a Rosetta Score. From these predictions, researchers hope to predict the function of the myriad proteins. This increased understanding of the human proteins could prove vital in the search for cures to human [[diseases]].<ref>{{cite web |url=http://www.worldcommunitygrid.org/projects_showcase/archives/viewHpfResearch.do |title=Human Proteome Folding Project |work=Research |publisher=World Community Grid |access-date=2007-08-04 |archive-date=2007-08-20 |archive-url=https://web.archive.org/web/20070820042136/http://www.worldcommunitygrid.org/projects_showcase/archives/viewHpfResearch.do |url-status=live }}</ref> Computing for this project was officially completed on July 18, 2006.<ref>{{cite web |url=http://www.worldcommunitygrid.org/projects_showcase/archives/viewHpfOverview.do |title=Human Proteome Folding Project Overview |work=Research |publisher=World Community Grid |access-date=2007-07-28 |archive-date=2007-07-14 |archive-url=https://web.archive.org/web/20070714022845/http://www.worldcommunitygrid.org/projects_showcase/archives/viewHpfOverview.do |url-status=live }}</ref> Research results for the yeast portion of HPF1 have been published.<ref>{{cite journal | vauthors = Malmström L, Riffle M, Strauss CE, Chivian D, Davis TN, Bonneau R, Baker D | title = Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology | journal = PLOS Biology | volume = 5 | issue = 4 | pages = e76 | date = April 2007 | pmid = 17373854 | pmc = 1828141 | doi = 10.1371/journal.pbio.0050076 | doi-access = free }}</ref>
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)