Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
Chemical synapse
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
==Relationship to electrical synapses== An [[electrical synapse]] is an electrically [[electrical conductor|conductive]] link between two abutting [[neuron]]s that is formed at a narrow gap between the pre- and postsynaptic [[cell (biology)|cell]]s, known as a [[gap junction]]. At gap junctions, cells approach within about 3.5 [[Nanometre|nm]] of each other, rather than the 20 to 40 nm distance that separates cells at chemical synapses.<ref>{{harvnb|Kandel|Schwartz|Jessell|2000|p=176}}</ref><ref>{{harvnb|Hormuzdi|Filippov|Mitropoulou|Monyer|Bruzzone|2004}}</ref> As opposed to chemical synapses, the postsynaptic potential in electrical synapses is not caused by the opening of ion channels by chemical transmitters, but rather by direct electrical coupling between both neurons. Electrical synapses are faster than chemical synapses.<ref name="KandelPrin"/> Electrical synapses are found throughout the nervous system, including in the [[retina]], the [[reticular nucleus of the thalamus]], the [[neocortex]], and in the [[hippocampus]].<ref>{{cite journal |vauthors=Connors BW, Long MA |title=Electrical synapses in the mammalian brain |journal=Annu. Rev. Neurosci. |volume=27 |issue= 1|pages=393β418 |year=2004 |pmid=15217338 |doi=10.1146/annurev.neuro.26.041002.131128 |url=https://zenodo.org/record/894386 }}</ref> While chemical synapses are found between both excitatory and inhibitory neurons, electrical synapses are most commonly found between smaller local inhibitory neurons. Electrical synapses can exist between two axons, two dendrites, or between an axon and a dendrite.<ref>{{cite journal |vauthors=Veruki ML, Hartveit E |title=Electrical synapses mediate signal transmission in the rod pathway of the mammalian retina |journal=J. Neurosci. |volume=22 |issue=24 |pages=10558β66 |date=December 2002 |pmid=12486148|pmc=6758447 |doi=10.1523/JNEUROSCI.22-24-10558.2002 }} </ref><ref>{{cite journal |vauthors=Bennett MV, Pappas GD, Aljure E, Nakajima Y |title=Physiology and ultrastructure of electrotonic junctions. II. Spinal and medullary electromotor nuclei in mormyrid fish |journal=J. Neurophysiol. |volume=30 |issue=2 |pages=180β208 |date=March 1967 |pmid=4167209 |doi=10.1152/jn.1967.30.2.180 }}</ref> In some [[fish]] and [[amphibian]]s, electrical synapses can be found within the same terminal of a chemical synapse, as in [[Mauthner cells]].<ref>{{cite journal |vauthors=Pereda AE, Rash JE, Nagy JI, Bennett MV |title=Dynamics of electrical transmission at club endings on the Mauthner cells |journal=Brain Res. Brain Res. Rev. |volume=47 |issue=1β3 |pages=227β44 |date=December 2004 |pmid=15572174 |doi=10.1016/j.brainresrev.2004.06.010 |citeseerx=10.1.1.662.9352 |s2cid=9527518 }}</ref>
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)