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Claustrum
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=== Psilocybin === The claustrum expresses a high density of [[5-HT2A receptor|5-HT<sub>2A</sub> receptors]], meaning it is significantly affected by [[serotonergic psychedelics]] like [[psilocybin]]. Psilocybin appears to affect the functional connectivity of the claustrum with the [[default mode network]] (DMN), and the fronto-parietal task control network (FPTC). Psilocybin was found to significantly decrease functional connectivity of the right claustrum with the default mode network, and increase right claustrum connectivity with the fronto-parietal task control network.<ref>{{Cite journal |last1=Barrett |first1=Frederick S. |last2=Krimmel |first2=Samuel R. |last3=Griffiths |first3=Roland R. |last4=Seminowicz |first4=David A. |last5=Mathur |first5=Brian N. |date=September 2020 |title=Psilocybin acutely alters the functional connectivity of the claustrum with brain networks that support perception, memory, and attention |journal=NeuroImage |volume=218 |pages=116980 |doi=10.1016/j.neuroimage.2020.116980 |issn=1095-9572 |pmid=32454209|doi-access=free |pmc=10792549 }}</ref>
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