Editing Clostridium perfringens (section)

==== Fucosidase ====
[[Fucose]] monosaccharides are located on the terminal ends of core O-linked glycans. ''C. perfringens'' encodes for three fucosidases that belong to two glycoside hydrolase families: Afc1 and Afc2 in [[glycoside hydrolase family 29]] (GH29), and Afc3 in glycoside hydrolase family 95 (GH95). Afc3 contains a C-terminal CBM51 and is the only fucosidase that contains a carbohydrate-binding module in ''C. perfringens''. Fucosyl residues tend to cover the ends of glycans and protect them against enzymatic digestion, so research suggests that the ability of fucosidases to cleave complex and diverse fucosyl linkages is due to long-term adaptations in ''C. perfringens'' that persisted within close range of mucins.<ref name=":022" />