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Gene duplication
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===Genomic microarrays detect duplications=== Technologies such as genomic [[microarrays]], also called array comparative [[genomic]] hybridization (array CGH), are used to detect chromosomal abnormalities, such as microduplications, in a high throughput fashion from genomic DNA samples. In particular, DNA [[microarray]] technology can simultaneously monitor the [[gene expression|expression]] levels of thousands of genes across many treatments or experimental conditions, greatly facilitating the evolutionary studies of [[gene regulation]] after gene duplication or [[speciation]].<ref>{{cite journal | vauthors = Mao R, Pevsner J | title = The use of genomic microarrays to study chromosomal abnormalities in mental retardation | journal = Mental Retardation and Developmental Disabilities Research Reviews | volume = 11 | issue = 4 | pages = 279β85 | year = 2005 | pmid = 16240409 | doi = 10.1002/mrdd.20082 }}</ref><ref>{{cite journal | vauthors = Gu X, Zhang Z, Huang W | title = Rapid evolution of expression and regulatory divergences after yeast gene duplication | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 3 | pages = 707β12 | date = January 2005 | pmid = 15647348 | pmc = 545572 | doi = 10.1073/pnas.0409186102 | bibcode = 2005PNAS..102..707G | doi-access = free }}</ref>
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