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Repeated sequence (DNA)
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=== Amyotrophic lateral sclerosis and Frontotemporal dementia === Not all diseases caused by repeated DNA sequences are trinucleotide repeat diseases. The diseases [[amyotrophic lateral sclerosis]] and [[frontotemporal dementia]] are caused by hexanucleotide GGGGCC repeat sequences in the ''[[C9orf72]]'' gene, causing RNA toxicity that leads to neurodegeneration.<ref>{{cite journal | vauthors = van Blitterswijk M, DeJesus-Hernandez M, Rademakers R | title = How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: can we learn from other noncoding repeat expansion disorders? | journal = Current Opinion in Neurology | volume = 25 | issue = 6 | pages = 689β700 | date = December 2012 | pmid = 23160421 | pmc = 3923493 | doi = 10.1097/WCO.0b013e32835a3efb }}</ref><ref name="Abugable2019" />
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