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Suprachiasmatic nucleus
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==History== The idea that the SCN is the main sleep cycle regulator in mammals was proposed by [[Robert Y. Moore|Robert Moore]], who conducted experiments using radioactive [[amino acid]]s to find where the termination of the [[Retinohypothalamic tract|retinohypothalamic projection]] occurs in rodents.<ref name="Klein">{{Cite book |last1=Klein |first1=David C. |url=https://books.google.com/books?id=8fgwFsmTBwgC&dq=suprachiasmatic+nucleus&pg=PR16 |title=Suprachiasmatic Nucleus: The Mind's Clock |last2=Moore |first2=Robert Y. |last3=Reppert |first3=Steven M. |date=1991 |publisher=Oxford University Press |isbn=978-0-19-506250-2 |language=en}}</ref><ref>{{Citation |last=Moore |first=Robert Y. |title=Chapter One - The Suprachiasmatic Nucleus and the Circadian Timing System |date=2013-01-01 |url=https://www.sciencedirect.com/science/article/pii/B9780123969712000014 |journal=Progress in Molecular Biology and Translational Science |volume=119 |pages=1β28 |editor-last=Gillette |editor-first=Martha U. |access-date=2023-04-25 |series=Chronobiology: Biological Timing in Health and Disease |publisher=Academic Press |doi=10.1016/B978-0-12-396971-2.00001-4 |pmid=23899592 |language=en|url-access=subscription }}</ref> Early lesioning experiments in mouse, guinea pig, cat, and opossum established how removal of the SCN results in ablation of circadian rhythm in mammals.<ref name="Klein" />
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