Editing Transient receptor potential channel (section)

=== Group 2 Characteristics ===
Group two most distinguishable trait is the long extracellular span between the S1 and S2 transmembrane segments. Members of group two are also lacking in ankryin repeats and a TRP domain. They have been shown, however, to have endoplasmic reticulum (ER) retention sequences towards on the C-terminal end illustrating possible interactions with the ER.<ref name="Kadowaki_evodyn"/><ref name=":3" /><ref name=":4" />