Editing Ulcerative colitis (section)

===Histologic===
[[Image:Ulcerative colitis (2) endoscopic biopsy.jpg|thumb|left|Biopsy sample ([[H&E stain]]) that demonstrates marked [[lymphocyte|lymphocytic]] infiltration (blue/purple) of the [[intestinal mucosa]] and architectural distortion of the crypts.]]
[[File:Histopathology of a crypt abscess.jpg|thumb|Crypt abscess. H&E stain.]]
[[Biopsy|Biopsies]] of the mucosa are taken during endoscopy to confirm the diagnosis of UC and differentiate it from Crohn's disease, which is managed differently clinically. Histologic findings in ulcerative colitis includes: distortion of [[Intestinal crypt|crypt]] architecture, crypt abscesses, and inflammatory cells in the mucosa (lymphocytes, plasma cells, and granulocytes).<ref name="Feuerstein_UC" /> Unlike the transmural inflammation seen in Crohn's disease, the inflammation of ulcerative colitis is limited to the mucosa.<ref name="Feuerstein_UC" />