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C-reactive protein
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=== Obstructive sleep apnea === C-reactive protein (CRP), a marker of systemic inflammation, is also increased in [[obstructive sleep apnea]] (OSA). CRP and interleukin-6 (IL-6) levels were significantly higher in patients with OSA compared to obese control subjects.<ref name="pmid23533751">{{cite journal | vauthors = Latina JM, Estes NA, Garlitski AC | title = The Relationship between Obstructive Sleep Apnea and Atrial Fibrillation: A Complex Interplay | journal = Pulmonary Medicine | volume = 2013 | pages = 621736 | year = 2013 | pmid = 23533751 | pmc = 3600315 | doi = 10.1155/2013/621736 | doi-access = free }}</ref> Patients with OSA have higher plasma CRP concentrations that increased corresponding to the severity of their [[apnea-hypopnea index]] score. Treatment of OSA with CPAP ([[continuous positive airway pressure]]) significantly alleviated the effect of OSA on CRP and IL-6 levels.<ref name="pmid23533751"/>
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