Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
Chemical synapse
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
==Effects of drugs== {{Main|Neuropharmacology}} One of the most important features of chemical synapses is that they are the site of action for the majority of [[psychoactive drugs]]. Synapses are affected by drugs, such as curare, strychnine, cocaine, morphine, alcohol, LSD, risperidone, and countless others. These drugs have different effects on synaptic function, and often are restricted to synapses that use a specific neurotransmitter. For example, [[curare]] is a poison that stops [[acetylcholine]] from depolarizing the postsynaptic membrane, causing [[paralysis]]. [[Strychnine]] blocks the inhibitory effects of the neurotransmitter [[glycine]], which causes the body to pick up and react to weaker and previously ignored stimuli, resulting in uncontrollable [[muscle spasms]]. [[Morphine]] acts on synapses that use [[endorphin]] neurotransmitters, and [[alcohol (drug)|alcohol]] increases the inhibitory effects of the neurotransmitter [[GABA]]. [[LSD]] interferes with synapses that use the neurotransmitter [[serotonin]]. [[Risperidone]] is a blocker of various receptors including several dopamine and serotonin receptors, and it can bind with high affinity to some types of serotonin receptors. [[Cocaine]] blocks reuptake of [[dopamine]] and therefore increases its effects.
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)