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Clarithromycin
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===Calcium channel blockers=== Concurrent therapy with [[calcium channel blocker]] may increase risk of [[Hypotension|low blood pressure]], [[kidney failure]], and death, compared to pairing calcium channel blockers with [[azithromycin]], a drug similar to clarithromycin but without CYP3A4 inhibition.<ref name="pmid24346990">{{cite journal | vauthors = Gandhi S, Fleet JL, Bailey DG, McArthur E, Wald R, Rehman F, Garg AX | title = Calcium-channel blocker-clarithromycin drug interactions and acute kidney injury | journal = JAMA | volume = 310 | issue = 23 | pages = 2544β53 | date = December 2013 | pmid = 24346990 | doi = 10.1001/jama.2013.282426 | doi-access = }}</ref> Administration of clarithromycin in combination with verapamil have been observed to cause [[Hypotension|low blood pressure]], [[Bradycardia|low heart rate]], and [[lactic acidosis]].<ref name="biaxin-filmtab" />
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