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Drug interaction
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==Epidemiology== As of 2008, among adults in the [[United States of America]] older than 56, 4% were taking medication and/ or supplements that put them at risk of a major drug interaction.<ref>{{cite journal | vauthors = Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P, Lindau ST | title = Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States | journal = JAMA | volume = 300 | issue = 24 | pages = 2867β78 | date = December 2008 | pmid = 19109115 | pmc = 2702513 | doi = 10.1001/jama.2008.892 }}</ref> Potential drug-drug interactions have increased over time<ref name="pmid18184532">{{cite journal | vauthors = Haider SI, Johnell K, Thorslund M, Fastbom J | title = Trends in polypharmacy and potential drug-drug interactions across educational groups in elderly patients in Sweden for the period 1992 - 2002 | journal = International Journal of Clinical Pharmacology and Therapeutics | volume = 45 | issue = 12 | pages = 643β53 | date = December 2007 | pmid = 18184532 | doi = 10.5414/cpp45643 }}</ref> and are more common in the less-educated [[elderly]] even after controlling for age, sex, place of residence, and [[comorbidity]].<ref name="pmid19054196">{{cite journal | vauthors = Haider SI, Johnell K, Weitoft GR, Thorslund M, Fastbom J | title = The influence of educational level on polypharmacy and inappropriate drug use: a register-based study of more than 600,000 older people | journal = Journal of the American Geriatrics Society | volume = 57 | issue = 1 | pages = 62β9 | date = January 2009 | pmid = 19054196 | doi = 10.1111/j.1532-5415.2008.02040.x | s2cid = 205703844 }}</ref>
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