Editing Laboratory mouse (section)

===Injection procedures===
[[Routes of administration]] of injections in laboratory mice are mainly [[subcutaneous administration|subcutaneous]], [[intraperitoneal administration|intraperitoneal]] and [[intravenous administration|intravenous]]. [[Intramuscular administration]] is not recommended due to small muscle mass.<ref name="duke">{{cite web|title=Guidelines for Selecting Route and Needle Size|url=http://vetmed.duhs.duke.edu/guidelines_for_needle_size_volume.htm|publisher=Duke University and Medical Center – Animal Care & Use Program|access-date=8 April 2011|archive-url=https://web.archive.org/web/20100609221642/http://vetmed.duhs.duke.edu/guidelines_for_needle_size_volume.htm|archive-date=9 June 2010}}</ref> [[Intracerebral administration]] is also possible. Each route has a recommended injection site, approximate [[Needle gauge comparison chart|needle gauge]] and recommended maximum injected volume at a single time at one site, as given in the table below:
{|class="wikitable"
! [[Routes of administration|Route]] !! Recommended site<ref name="duke"/> !! [[Needle gauge comparison chart|Needle gauge]]<ref name=duke/> || Maximal volume<ref name=drexel>[http://www.drexelmed.edu/documents/ULAR/IACUC_drugs.pdf A Compendium of Drugs Used for Laboratory Animal Anesthesia, Analgesia, Tranquilization and Restraint] {{webarchive|url=https://web.archive.org/web/20110606212907/http://www.drexelmed.edu/documents/ULAR/IACUC_drugs.pdf |date=2011-06-06 }} at Drexel University College of Medicine. Retrieved April 2011</ref>
|-
| [[subcutaneous administration|subcutaneous]] || dorsum, between [[scapula]] || 25-26 [[Needle gauge comparison chart|ga]] || 2-3 [[millilitre|ml]]
|-
| [[intraperitoneal administration|intraperitoneal]] || [[left lower quadrant]] || 25-27 ga || 2-3 ml
|-
| [[intravenous administration|intravenous]] || [[lateral tail vein]]|| 27-28 ga || 0.2 ml
|-
| [[Intramuscular administration|intramuscular]] || hindlimb, caudal thigh || 26-27 ga || 0.05 ml
|-
| [[Intracerebral administration|intracerebral]]|| cranium || 27 ga
|}
To facilitate intravenous injection into the tail, laboratory mice can be carefully warmed under heat lamps to [[vasodilate]] the vessels.<ref name=duke/>