Editing Longevity (section)

=== Artificial animal longevity extension ===
[[CRISPR gene editing|Gene editing]] via [[CRISPR]]-[[Cas9]] and other methods have significantly altered lifespans in animals.<ref>{{cite journal | vauthors = Kenyon C | title = The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing | journal = Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences | volume = 366 | issue = 1561 | pages = 9–16 | date = January 2011 | pmid = 21115525 | pmc = 3001308 | doi = 10.1098/rstb.2010.0276 }}</ref><ref>{{cite journal | vauthors = Ekman FK, Ojala DS, Adil MM, Lopez PA, Schaffer DV, Gaj T | title = CRISPR-Cas9-Mediated Genome Editing Increases Lifespan and Improves Motor Deficits in a Huntington's Disease Mouse Model | language = English | journal = Molecular Therapy: Nucleic Acids | volume = 17 | pages = 829–839 | date = September 2019 | pmid = 31465962 | pmc = 6717077 | doi = 10.1016/j.omtn.2019.07.009 }}</ref><ref>{{Citation| vauthors = Haston S, Pozzi S, Gonzalez-Meljem JM |title=Applications of CRISPR-Cas in Ageing Research|date=2020 |work=Clinical Genetics and Genomics of Aging|pages=213–230| veditors = Gomez-Verjan JC, Rivero-Segura NA |place=Cham|publisher=Springer |doi=10.1007/978-3-030-40955-5_11|isbn=978-3-030-40955-5 |s2cid=218805944 }}</ref>