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Macadamia
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===Allergen=== Macadamia allergy is a type of [[food allergy]] to macadamia nuts which is relatively rare, affecting less than 5% of people with [[tree nut allergy]] in the United States.<ref name="Cox">{{cite journal |last1=Cox |first1=A.L. |last2=Eigenmann |first2=P.A. |last3=Sicherer |first3=S.H. |date=2021 |title=Clinical Relevance of Cross-Reactivity in Food Allergy |url=https://www.jaci-inpractice.org/article/S2213-2198(20)31008-4/fulltext |journal=The Journal of Allergy and Clinical Immunology: In Practice |volume=9 |issue=1 |pages=82β99 |doi=10.1016/j.jaip.2020.09.030 |pmid=33429724 |s2cid=231587027 |access-date=6 May 2023|url-access=subscription }}</ref> Macadamia allergy can cause mild to severe allergic reactions, such as [[oral allergy syndrome]], [[urticaria]], [[angioedema]], vomiting, abdominal pain, [[asthma]], and [[anaphylaxis]].<ref name="Yoshida">{{cite journal |last1=Yoshida |first1=K |last2=Shirane |first2=S |last3=Kinoshita |first3=K |date=2021 |title=Macadamia nut allergy in children: Clinical features and cross-reactivity with walnut and hazelnut. |url=https://onlinelibrary.wiley.com/doi/10.1111/pai.13469 |journal=Pediatric Allergy and Immunology |volume=32 |issue=5 |pages=111β1114 |doi=10.1111/pai.13469 |pmid=33559377 |s2cid=231863665 |access-date=6 May 2023|url-access=subscription }}</ref> Macadamia allergy can also cross-react with other tree nuts or foods that have similar allergenic proteins, such as [[coconut]], [[walnut]], [[hazelnut]], and [[cashew]].<ref name="f345">{{cite web |title=f345 Macadamia nut |url=https://www.thermofisher.com/diagnostic-education/hcp/gb/en/resource-center/allergen-encyclopedia/whole-allergens.html?key=f345 |access-date=6 May 2023 |website=Allergy & Autoimmune Disease}}</ref> The diagnosis and management of macadamia allergy involves avoiding macadamia nuts and their derivatives, reading food labels carefully, carrying an [[epinephrine auto-injector]] in case of severe reactions, and consulting a doctor for further testing and advice.
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