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Optical coherence tomography
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=== Neurovascular === {{main|Intravascular optical coherence tomography}} Endoscopic/intravascular OCT has been further developed for use in neurovascular applications including imaging for guiding endovascular treatment of ischemic stroke and brain aneurysms.<ref>{{Cite journal |last1=Gounis |first1=Matthew J. |last2=Ughi |first2=Giovanni J. |last3=Marosfoi |first3=Miklos |last4=Lopes |first4=Demetrius K. |last5=Fiorella |first5=David |last6=Bezerra |first6=Hiram G. |last7=Liang |first7=Conrad W. |last8=Puri |first8=Ajit S. |date=January 2019 |title=Intravascular Optical Coherence Tomography for Neurointerventional Surgery |journal=Stroke |volume=50 |issue=1 |pages=218β223 |doi=10.1161/STROKEAHA.118.022315|pmid=30580737 |pmc=6541539 }}</ref><ref>{{cite journal | vauthors = Chen CJ, Kumar JS, Chen SH, Ding D, Buell TJ, Sur S, Ironside N, Luther E, Ragosta M, Park MS, Kalani MY, Liu KC, Starke RM | display-authors = 6 | title = Optical Coherence Tomography: Future Applications in Cerebrovascular Imaging | journal = Stroke | volume = 49 | issue = 4 | pages = 1044β1050 | date = April 2018 | pmid = 29491139 | doi = 10.1161/STROKEAHA.117.019818 | doi-access = free }}</ref> Initial clinical investigations with existing coronary OCT catheters have been limited to proximal intracranial anatomy of patient with limited tortuosity, as coronary OCT technology was not designed for the tortuous cerebrovasculature encountered in the brain. However, despite these limitations, it showed the potential of OCT for the imaging of neurovascular disease.<ref>{{cite journal | vauthors = Xu X, Li M, Liu R, Yin Q, Shi X, Wang F, Gao J, Xu G, Ye R, Liu X | display-authors = 6 | title = Optical coherence tomography evaluation of vertebrobasilar artery stenosis: case series and literature review | journal = Journal of NeuroInterventional Surgery | volume = 12 | issue = 8 | pages = 809β813 | date = August 2020 | pmid = 32066569 | doi = 10.1136/neurintsurg-2019-015660 | s2cid = 211159079 }}</ref> An intravascular OCT imaging catheter design tailored for use in tortuous neurovascular anatomy has been proposed in 2020.<ref>{{cite journal | vauthors = Ughi GJ, Marosfoi MG, King RM, Caroff J, Peterson LM, Duncan BH, Langan ET, Collins A, Leporati A, Rousselle S, Lopes DK, Gounis MJ, Puri AS | display-authors = 6 | title = A neurovascular high-frequency optical coherence tomography system enables in situ cerebrovascular volumetric microscopy | journal = Nature Communications | volume = 11 | issue = 1 | pages = 3851 | date = July 2020 | pmid = 32737314 | pmc = 7395105 | doi = 10.1038/s41467-020-17702-7 | bibcode = 2020NatCo..11.3851U }}</ref> A first-in-human study using endovascular neuro OCT (''n''OCT) has been reported in 2024.<ref>{{Cite journal |last1=Pereira |first1=Vitor M. |last2=Lylyk |first2=Pedro |last3=Cancelliere |first3=Nicole |last4=Lylyk |first4=Pedro N. |last5=Lylyk |first5=Ivan |last6=Anagnostakou |first6=Vania |last7=Bleise |first7=Carlos |last8=Nishi |first8=Hidehisa |last9=Epshtein |first9=Mark |last10=King |first10=Robert M. |last11=Shazeeb |first11=Mohammed Salman |last12=Puri |first12=Ajit S. |last13=Liang |first13=Conrad W. |last14=Hanel |first14=Ricardo A. |last15=Spears |first15=Julian |date=2024-05-15 |title=Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe |url=https://www.science.org/doi/10.1126/scitranslmed.adl4497 |journal=Science Translational Medicine |language=en |volume=16 |issue=747 |pages=eadl4497 |doi=10.1126/scitranslmed.adl4497 |pmid=38748771 |issn=1946-6234|url-access=subscription }}</ref><ref>{{Cite journal |last1=Siddiqui |first1=Adnan H |last2=Andersson |first2=Tommy |date=2024-09-26 |title=Shining light on neurovascular disease |journal=Interventional Neuroradiology |language=en |pages=15910199241285962 |doi=10.1177/15910199241285962 |issn=1591-0199 |pmc=11559757 |pmid=39324217}}</ref><ref>{{Cite web |title="Snake-like" Probe Images Arteries from Within - IEEE Spectrum |url=https://spectrum.ieee.org/fiber-optic-probe |access-date=2024-05-17 |website=[[IEEE]] |language=en}}</ref>
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