Editing Plant hormone (section)

==Human use==

===Salicylic acid===
Willow bark has been used for centuries as a painkiller. The active ingredient in willow bark that provides these effects is the hormone [[salicylic acid]] (SA). In 1899, the pharmaceutical company Bayer began marketing a derivative of SA as the drug [[aspirin]].<ref>{{cite book |title=Aspirin : the remarkable story of a wonder drug| vauthors = Diarmuid J |isbn=9781596918160 |location=New York, NY |oclc=879610692 |date=December 2008 }}</ref> In addition to its use as a painkiller, SA is also used in topical treatments of several skin conditions, including acne, warts and psoriasis.<ref>{{cite journal | vauthors = Madan RK, Levitt J | title = A review of toxicity from topical salicylic acid preparations | language = en | journal = Journal of the American Academy of Dermatology | volume = 70 | issue = 4 | pages = 788–792 | date = April 2014 | pmid = 24472429 | doi = 10.1016/j.jaad.2013.12.005 }}</ref> Another derivative of SA, [[sodium salicylate]] has been found to suppress proliferation of lymphoblastic leukemia, prostate, breast, and melanoma human cancer cells.<ref name="Fingrut-2002">{{cite journal | vauthors = Fingrut O, Flescher E | title = Plant stress hormones suppress the proliferation and induce apoptosis in human cancer cells | journal = Leukemia | volume = 16 | issue = 4 | pages = 608–16 | date = April 2002 | pmid = 11960340 | doi = 10.1038/sj.leu.2402419 | doi-access = free }}</ref>

===Jasmonic acid===
[[Jasmonic acid]] (JA) can induce death in [[acute lymphoblastic leukemia|lymphoblastic leukemia]] cells. [[Methyl jasmonate]] (a derivative of JA, also found in plants) has been shown to inhibit proliferation in a number of cancer cell lines,<ref name="Fingrut-2002" /> although there is still debate over its use as an anti-cancer drug, due to its potential negative effects on healthy cells.<ref>{{cite journal | vauthors = Zhang M, Zhang MW, Zhang L, Zhang L | title = Methyl jasmonate and its potential in cancer therapy | journal = Plant Signaling & Behavior | volume = 10 | issue = 9 | pages = e1062199 | date = 2015-07-24 | pmid = 26208889 | pmc = 4883903 | doi = 10.1080/15592324.2015.1062199 | bibcode = 2015PlSiB..10E2199Z }}</ref>