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Propranolol
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==History== {{Main|Discovery and development of Ξ²-adrenergic receptor antagonists (beta-blockers)}} [[Scottish people|Scottish]] scientist [[James W. Black]] developed propranolol in the 1960s.<ref name="Black JW, Crowther AF, Shanks RG, Smith LH, Dornhorst AC 1964 1080β1081">{{cite journal | vauthors = Black JW, Crowther AF, Shanks RG, Smith LH, Dornhorst AC | title = A New Adrenergic Beta-Receptor Antagonist | journal = Lancet | volume = 1 | issue = 7342 | pages = 1080β1081 | date = May 1964 | pmid = 14132613 | doi = 10.1016/S0140-6736(64)91275-9 }}</ref> It was the first beta-blocker effectively used in the treatment of [[coronary artery disease]] and [[hypertension]].<ref name=":0">{{Cite book|title=Basic & Clinical Pharmacology| vauthors = Benowitz NL |publisher=McGraw-Hill|year=2017|isbn=9781259641152| veditors = Katzung BG |edition=14th|chapter=Antihypertensive Agents}}</ref> Newer, more cardio-selective beta blockers (such as [[bisoprolol]], [[nebivolol]], [[carvedilol]], or [[metoprolol]]) are used preferentially in the treatment of [[hypertension]].<ref name=":0" />
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