Editing Structural bioinformatics (section)

=== ''De novo'' modeling ===
In structural bioinformatics, [[De novo protein structure prediction|''de novo'' modeling]], also known as ''ab initio'' modeling, refers to approaches for obtaining three-dimensional structures from sequences without the necessity of a homologous known 3D structure. Despite the new algorithms and methods proposed in the last years, de novo protein structure prediction is still considered one of the remain outstanding issues in modern science.<ref>{{cite journal | title = So much more to know | journal = Science | volume = 309 | issue = 5731 | pages = 78–102 | date = July 2005 | pmid = 15994524 | doi = 10.1126/science.309.5731.78b | doi-access = free }}</ref>