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Anovulation
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=== Treatment for hyperprolactinemia === For anovulatory women with hyperprolactinemia without symptoms, they can forgo treatment and continue with close follow up and medical observation.<ref name=":6" /> If symptoms of hyperprolactinemia are present, dopamine agonists, such as bromocriptine, are first line treatment which act by inhibiting production of [[prolactin]] by the pituitary and can shrink a prolactin-secretin lesion (i.e. prolactinoma) if present.<ref name="palomba2004">{{cite journal|author=Palomba S|author2=Orio F|author3=Nardo LG|last4=Falbo|first4=A|last5=Russo|first5=T|last6=Corea|first6=D|last7=Doldo|first7=P|last8=Lombardi|first8=G|last9=Tolino|first9=A|display-authors=3|name-list-style=vanc|date=October 2004|title=Metformin administration versus laparoscopic ovarian diathermy in clomiphene citrate-resistant women with polycystic ovary syndrome: a prospective parallel randomized double-blind placebo-controlled trial|journal=J. Clin. Endocrinol. Metab.|volume=89|issue=10|pages=4801β4809|doi=10.1210/jc.2004-0689|pmid=15472166|doi-access=free}}</ref> In rare cases, endoscopic transnasal transsphenoidal surgery and radiotherapy, may be required to resect and shrink a prolactinoma if greater than 10 mm in size. Importantly, individuals should be able to conceive following normalization of serum prolactin levels and shrinking or removal of the tumor.<ref name=":6" />
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