Editing Bilirubin (section)

=== Measurement methods ===
Originally, the [[Van den Bergh reaction]] was used for a qualitative estimate of bilirubin.{{cn|date=July 2024}}

This test is performed routinely in most [[Medical laboratory|medical laboratories]] and can be measured by a variety of methods.<ref>{{cite journal |vauthors=Watson D, Rogers JA |date=May 1961 |title=A study of six representative methods of plasma bilirubin analysis |journal=[[Journal of Clinical Pathology]] |volume=14 |issue=3 |pages=271–8 |doi=10.1136/jcp.14.3.271 |pmc=480210 |pmid=13783422}}</ref>

Total bilirubin is now often measured by the 2,5-dichlorophenyldiazonium (DPD) method, and direct bilirubin is often measured by the method of Jendrassik and Grof.<ref>{{cite journal |vauthors=Rolinski B, Küster H, Ugele B, Gruber R, Horn K |date=October 2001 |title=Total bilirubin measurement by photometry on a blood gas analyzer: potential for use in neonatal testing at the point of care |url=http://www.clinchem.org/cgi/pmidlookup?view=long&pmid=11568098 |journal=[[Clinical Chemistry (journal)|Clinical Chemistry]] |volume=47 |issue=10 |pages=1845–7 |doi=10.1093/clinchem/47.10.1845 |pmid=11568098 |doi-access=free}}</ref>