Editing Cannabinoid (section)

==== Modulation of mitochondrial activity ====
Evidence has shown that cannabinoids play a role in the modulation of various mitochondrial processes, including intracellular calcium regulation, activation of apoptosis, impairment of electron transport chain activity, disruption of mitochondrial respiration and ATP production, and regulation of mitochondrial dynamics. These processes contribute to various aspects of cellular biology and can be modified in response to external stimuli. The interaction between cannabinoids and mitochondria is complex, and various molecular mechanisms have been proposed, including direct effects on mitochondrial membranes and receptor-mediated effects. However, an integrated hypothesis of cannabinoids' actions on these processes has yet to be formulated due to conflicting data and the complexity of the pathways involved.<ref>{{Cite journal |last1=Malheiro |first1=Rui Filipe |last2=Carmo |first2=Helena |last3=Carvalho |first3=Félix |last4=Silva |first4=João Pedro |date=January 2023 |title=Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics |journal=Pharmacological Research |language=en |volume=187 |pages=106603 |doi=10.1016/j.phrs.2022.106603 |pmid=36516885 |s2cid=254581177 |doi-access=free }}</ref>