Editing Celecoxib (section)

===Psychiatry===
On the theory that inflammation plays a role in the pathogenesis of major mental disorders, celecoxib has been trialed for a number of psychiatric disorders, including [[major depression]], [[bipolar disorder]], and [[schizophrenia]].<ref name="repurposed2021">{{cite journal | vauthors = Bartoli F, Cavaleri D, Bachi B, Moretti F, Riboldi I, Crocamo C, Carrà G | title = Repurposed drugs as adjunctive treatments for mania and bipolar depression: A meta-review and critical appraisal of meta-analyses of randomized placebo-controlled trials | journal = Journal of Psychiatric Research | date = September 2021 | volume = 143 | pages = 230–238 | doi = 10.1016/j.jpsychires.2021.09.018| pmid = 34509090 | s2cid = 237485915 }}</ref><ref>{{cite journal | vauthors = Müller N, Myint AM, Krause D, Weidinger E, Schwarz MJ | title = Anti-inflammatory treatment in schizophrenia | journal = Progress in Neuro-Psychopharmacology & Biological Psychiatry | volume = 42 | pages = 146–53 | date = April 2013 | pmid = 23178230 | doi = 10.1016/j.pnpbp.2012.11.008 | s2cid = 22078590 }}</ref><ref name=":0">{{cite journal | vauthors = Na KS, Lee KJ, Lee JS, Cho YS, Jung HY | title = Efficacy of adjunctive celecoxib treatment for patients with major depressive disorder: a meta-analysis | journal = Progress in Neuro-Psychopharmacology & Biological Psychiatry | volume = 48 | pages = 79–85 | date = January 2014 | pmid = 24056287 | doi = 10.1016/j.pnpbp.2013.09.006 | s2cid = 35885429 }}</ref><ref>{{cite journal | vauthors = Rosenblat JD, Cha DS, Mansur RB, McIntyre RS | title = Inflamed moods: a review of the interactions between inflammation and mood disorders | journal = Progress in Neuro-Psychopharmacology & Biological Psychiatry | volume = 53 | pages = 23–34 | date = August 2014 | pmid = 24468642 | doi = 10.1016/j.pnpbp.2014.01.013 | s2cid = 32289214 }}</ref><ref>{{cite journal | vauthors = Fond G, Hamdani N, Kapczinski F, Boukouaci W, Drancourt N, Dargel A, Oliveira J, Le Guen E, Marlinge E, Tamouza R, Leboyer M | title = Effectiveness and tolerance of anti-inflammatory drugs' add-on therapy in major mental disorders: a systematic qualitative review | journal = Acta Psychiatrica Scandinavica | volume = 129 | issue = 3 | pages = 163–79 | date = March 2014 | pmid = 24215721 | doi = 10.1111/acps.12211 | s2cid=23482349 }}</ref>  A 2014 meta-analysis concluded that [[Combination therapy|adjunctive]] treatment with celecoxib improved depressive symptoms, response, and remission rates compared to placebo.<ref name=":0" />

====Bipolar disorder====
A meta-analysis considering trials of celecoxib as an adjunctive treatment in [[bipolar disorder]] was inconclusive citing low evidence quality.<ref name="repurposed2021"/>