Editing Exercise (section)

=== Central nervous system ===
{{Further|Neurobiological effects of physical exercise#Neuroplasticity}}
The effects of physical exercise on the [[central nervous system]] may be mediated in part by specific [[neurotrophic factor]] [[myokine|hormones released into the blood by muscles]], including [[brain-derived neurotrophic factor|BDNF]], [[insulin-like growth factor 1|IGF-1]], and [[vascular endothelial growth factor|VEGF]].<ref name="Exercise – neurotrophic factors + basal ganglia">{{cite journal | vauthors = Paillard T, Rolland Y, de Souto Barreto P | title = Protective Effects of Physical Exercise in Alzheimer's Disease and Parkinson's Disease: A Narrative Review | journal = Journal of Clinical Neurology | volume = 11 | issue = 3 | pages = 212–219 | date = July 2015 | pmid = 26174783 | pmc = 4507374 | doi = 10.3988/jcn.2015.11.3.212 | quote = }}</ref><ref name="BDNF meta analysis">{{cite journal | vauthors = Szuhany KL, Bugatti M, Otto MW | title = A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor | journal = Journal of Psychiatric Research | volume = 60 | pages = 56–64 | date = January 2015 | pmid = 25455510 | pmc = 4314337 | doi = 10.1016/j.jpsychires.2014.10.003 | quote =}}</ref><ref name="Cerebral hemodynamics and AD">{{cite journal | vauthors = Tarumi T, Zhang R | title = Cerebral hemodynamics of the aging brain: risk of Alzheimer disease and benefit of aerobic exercise | journal = Frontiers in Physiology | volume = 5 | pages = 6 | date = January 2014 | pmid = 24478719 | pmc = 3896879 | doi = 10.3389/fphys.2014.00006 | quote = | doi-access = free }}</ref>