Editing Prostate-specific antigen (section)

===Complexed PSA===

PSA exists in serum in the free (unbound) form and in a complex with [[alpha 1-antichymotrypsin]]; research has been conducted to see if measurements of complexed PSA are more specific and sensitive biomarkers for prostate cancer than other approaches.<ref name="Mikolajczyk-2002">{{cite journal | vauthors = Mikolajczyk SD, Marks LS, Partin AW, Rittenhouse HG | title = Free prostate-specific antigen in serum is becoming more complex | journal = Urology | volume = 59 | issue = 6 | pages = 797–802 | date = June 2002 | pmid = 12031356 | doi = 10.1016/S0090-4295(01)01605-3 }}</ref><ref name="Naya-2004">{{cite journal | vauthors = Naya Y, Okihara K | title = Role of complexed PSA in the early detection of prostate cancer | journal = Journal of the National Comprehensive Cancer Network | volume = 2 | issue = 3 | pages = 209–212 | date = May 2004 | pmid = 19795605 | doi = 10.6004/jnccn.2004.0019 | doi-access = free }}</ref>