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Protein structure
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==Protein structure databases== A [[protein structure database]] is a database that is [[data modeling|modeled]] around the various [[#Protein structure determination|experimentally determined]] protein structures. The aim of most protein structure databases is to organize and annotate the protein structures, providing the biological community access to the experimental data in a useful way. Data included in protein structure databases often includes 3D coordinates as well as experimental information, such as unit cell dimensions and angles for [[X-ray crystallography#Biological macromolecular crystallography|x-ray crystallography]] determined structures. Though most instances, in this case either proteins or a specific structure determinations of a protein, also contain sequence information and some databases even provide means for performing sequence based queries, the primary attribute of a structure database is structural information, whereas [[sequence database]]s focus on sequence information, and contain no structural information for the majority of entries. Protein structure databases are critical for many efforts in [[computational biology]] such as [[Drug design#Structure-based|structure based drug design]], both in developing the computational methods used and in providing a large experimental dataset used by some methods to provide insights about the function of a protein.<ref>{{cite journal | vauthors = Laskowski RA | title = Protein structure databases | journal = Molecular Biotechnology | volume = 48 | issue = 2 | pages = 183β198 | date = June 2011 | pmid = 21225378 | doi = 10.1007/s12033-010-9372-4 | s2cid = 45184564 }}</ref>
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