Editing Testicle (section)

===Effects of exogenous hormones===
To some extent, it is possible to change testicular size. Short of direct injury or subjecting them to adverse conditions, e.g., higher temperature than they are normally accustomed to, they can be shrunk by competing against their intrinsic hormonal function through the use of externally administered [[steroidal]] hormones. Steroids taken for muscle enhancement (especially [[anabolic steroids]]) often have the undesired side effect of testicular shrinkage.

Stimulation of testicular functions via [[gonadotropin|gonadotropic-like hormones]] may enlarge their size. Testes may shrink or atrophy during [[Hormone therapy|hormone replacement therapy]] or through [[chemical castration]].

In all cases, the loss in testes volume corresponds with a loss of spermatogenesis.