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Transdermal patch
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=== Advantages === [[File:Medical waste sorting in hospital.jpg|thumb|Disposing needlestick might cause injuries and transmission of pathogen.<ref>{{Cite journal|last=Rosenkranz|first=Cora|date=2021|title=Netzwerk- und Energiemanagement in Rechenzentren|journal=Technische Sicherheit|volume=11|issue=1–02|pages=20–21|doi=10.37544/2191-0073-2021-01-02-20|s2cid=234172001 |issn=2191-0073}}</ref>]] # The MNPs may puncture the skin surface, enabling rapid onset of drug bypassing directly into the dermal capillaries.<ref name=":2"/> # Pain-free. # Can be localized to provide direct access to the intended tissues.<ref name=":2" /> # Less dependent on skilled medical workers, as MNPs can be administered safely by the patient themself.<ref name=":2" /> # Some drugs have poor solubility in water, with MNPs insoluble drugs and compounds can be directly "injected" to the dermal layer. Further enhancing the transdermal delivery of insoluble drugs.<ref name="Kearney 605">{{Cite journal|last1=Kearney|first1=Mary-Carmel|last2=McKenna|first2=Peter E.|last3=Quinn|first3=Helen L.|last4=Courtenay|first4=Aaron J.|last5=Larrañeta|first5=Eneko|last6=Donnelly|first6=Ryan F.|date=2019-11-13|title=Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules|journal=Pharmaceutics|volume=11|issue=11|page=605|doi=10.3390/pharmaceutics11110605|pmid=31766145 |pmc=6920785|issn=1999-4923|doi-access=free }}</ref> # Better safety compared to needle and syringe method (needlestick). Less waste, eliminate pathogen transmission, and injuries. At least 300,000 needlestick related injuries occurred in the US annually, with disposal contribute to almost half of the injuries.<ref name="Kearney 605"/>
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