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Triptan
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===Legal status=== These drugs have been available only by prescription (US, Canada and UK), but sumatriptan became available over-the-counter in the UK in June 2006.<ref name="BBC_generic">{{cite web |publisher = BBC News |date = 2006-05-19 |title = Pharmacies to sell migraine drug |url = http://news.bbc.co.uk/1/hi/health/4996712.stm |access-date = 2006-09-05 |url-status = live |archive-url = https://web.archive.org/web/20060924041401/http://news.bbc.co.uk/1/hi/health/4996712.stm |archive-date = 2006-09-24 }}</ref> The brand name of the OTC product in the UK is Imigran Recovery. The patent on Imitrex STATDose expired in December 2006, and injectable sumatriptan became available as a generic formula in August 2008.{{Citation needed|date=April 2010}} Sumavel Dosepro is a needle-free delivery of injectable sumatriptan that was approved in the US by the FDA in July 2009.<ref name="Zogenix">{{cite web|url=http://www.zogenix.com/index.php/news/sumavel-dosepro-sumatriptan-injection-approved-by-fda-for-acute-migraine-and-cluster-headache/|title=Zogenix, Inc. - Therapeutic Solutions for CNS Disorders and Rare Disease|website=www.zogenix.com|access-date=6 May 2018|url-status=live|archive-url=https://web.archive.org/web/20160821125219/http://www.zogenix.com/index.php/news/sumavel-dosepro-sumatriptan-injection-approved-by-fda-for-acute-migraine-and-cluster-headache/|archive-date=21 August 2016}}</ref> Sumatriptan became available as a generic in the US in late 2009. It used to be sold over-the-counter in Romania under the Imigran brand; however, as of August 2014 prescription is required. Zecuity, a sumatriptan transdermal patch, was approved by the US FDA in January 2013.<ref name=":0" /> The sumatriptan nasal powder was approved by the FDA in January 2016 and became available in the U.S. May 2016.<ref>{{Cite web|url=http://www.avanir.com/press/avanir-pharmaceuticals-announces-fda-approval-onzetra%E2%84%A2-xsail%E2%84%A2-avp-825-acute-treatment-migraine|title=Avanir's press release: FDA approves Onzetra|date=January 28, 2016|website=Avanir Pharmaceuticals|access-date=May 20, 2016|url-status=live|archive-url=https://web.archive.org/web/20160511232617/http://www.avanir.com/press/avanir-pharmaceuticals-announces-fda-approval-onzetra%E2%84%A2-xsail%E2%84%A2-avp-825-acute-treatment-migraine|archive-date=May 11, 2016}}</ref> [[Naratriptan]] is available OTC in Germany and Brazil.
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