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Clostridium perfringens
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==== Beta toxin ==== Beta toxins (CPB) are a protein that causes hemorrhagic [[Clostridial necrotizing enteritis|necrotizing enteritis]] and [[Enterotoxemia|enterotoxaemia]] in both animals (type B) and humans (type C) which leads to the infected individual's feces becoming bloody and their intestines necrotizing.<ref name="Stiles-20132" /> [[Protease|Proteolytic enzymes]], such as trypsin, can break down CPB, making them ineffective. Therefore, the presence of trypsin inhibitors in colostrum makes CPB especially deadly for mammal offspring.<ref>{{Cite journal |last1=Garcia |first1=J.P. |last2=Beingesser |first2=J. |last3=Fisher |first3=D.J. |last4=Sayeed |first4=S. |last5=McClane |first5=B.A. |last6=Posthaus |first6=H. |last7=Uzal |first7=F.A. |date=4 January 2012 |title=The effect of Clostridium perfringens type C strain CN3685 and its isogenic beta toxin null mutant in goats |journal=Veterinary Microbiology |language=en |volume=157 |issue=3β4 |pages=412β419 |doi=10.1016/j.vetmic.2012.01.005 |pmc=3348370 |pmid=22296994}}</ref>
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