Editing Optical coherence tomography (section)

=== Dermatology ===
The first use of OCT in dermatology dates back to 1997.<ref>{{cite journal | vauthors = Welzel J, Lankenau E, Birngruber R, Engelhardt R | title = Optical coherence tomography of the human skin | journal = Journal of the American Academy of Dermatology | volume = 37 | issue = 6 | pages = 958–963 | date = December 1997 | pmid = 9418764 | doi = 10.1016/S0190-9622(97)70072-0 | s2cid = 20078741 | url = https://nbn-resolving.org/urn:nbn:de:bvb:384-opus4-906829 }}</ref> Since then, OCT has been applied to the diagnosis of various skin lesions including carcinomas.<ref>{{cite journal | vauthors = Boone MA, Norrenberg S, Jemec GB, Del Marmol V | title = Imaging of basal cell carcinoma by high-definition optical coherence tomography: histomorphological correlation. A pilot study | journal = The British Journal of Dermatology | volume = 167 | issue = 4 | pages = 856–864 | date = October 2012 | pmid = 22862425 | doi = 10.1111/j.1365-2133.2012.11194.x | s2cid = 24965088 }}</ref><ref>{{cite journal | vauthors = Coleman AJ, Richardson TJ, Orchard G, Uddin A, Choi MJ, Lacy KE | title = Histological correlates of optical coherence tomography in non-melanoma skin cancer | journal = Skin Research and Technology | volume = 19 | issue = 1 | pages = 10–19 | date = February 2013 | pmid = 22738357 | doi = 10.1111/j.1600-0846.2012.00626.x | s2cid = 26084419 }}</ref><ref>{{cite journal | vauthors = Ulrich M, von Braunmuehl T, Kurzen H, Dirschka T, Kellner C, Sattler E, Berking C, Welzel J, Reinhold U | display-authors = 6 | title = The sensitivity and specificity of optical coherence tomography for the assisted diagnosis of nonpigmented basal cell carcinoma: an observational study | journal = The British Journal of Dermatology | volume = 173 | issue = 2 | pages = 428–435 | date = August 2015 | pmid = 25904111 | doi = 10.1111/bjd.13853 | doi-access = free }}</ref> However, the diagnosis of melanoma using conventional OCT is difficult, especially due to insufficient imaging resolution.<ref>{{cite journal | vauthors = Levine A, Wang K, Markowitz O | title = Optical Coherence Tomography in the Diagnosis of Skin Cancer | journal = Dermatologic Clinics | volume = 35 | issue = 4 | pages = 465–488 | date = October 2017 | pmid = 28886803 | doi = 10.1016/j.det.2017.06.008 }}</ref> Emerging high-resolution OCT techniques such as LC-OCT have the potential to improve the clinical diagnostic process, allowing for the early detection of malignant skin tumors – including melanoma – and a reduction in the number of surgical excisions of benign lesions.<ref name="Dubois 2018">{{cite journal | vauthors = Dubois A, Levecq O, Azimani H, Siret D, Barut A, Suppa M, Del Marmol V, Malvehy J, Cinotti E, Rubegni P, Perrot JL | display-authors = 6 | title = Line-field confocal optical coherence tomography for high-resolution noninvasive imaging of skin tumors | journal = Journal of Biomedical Optics | volume = 23 | issue = 10 | pages = 1–9 | date = October 2018 | pmid = 30353716 | doi = 10.1117/1.JBO.23.10.106007 | s2cid = 53023955 | bibcode = 2018JBO....23j6007D | doi-access = free }}  [[File:CC-BY icon.svg|50px]] This article contains quotations from this source, which is available under the [https://creativecommons.org/licenses/by/3.0/  Creative Commons Attribution 3.0 Unported (CC BY 3.0)] license.</ref> Other promising areas of application include the imaging of lesions where excisions are hazardous or impossible and the guidance of surgical interventions through identification of tumor margins.