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Self-adjoint operator
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=== Constant-coefficient operators === We next give the example of differential operators with [[constant coefficient]]s. Let : <math>P\left(\vec{x}\right) = \sum_\alpha c_\alpha x^\alpha </math> be a polynomial on '''R'''<sup>''n''</sup> with ''real'' coefficients, where Ξ± ranges over a (finite) set of [[multi-index|multi-indices]]. Thus : <math> \alpha = (\alpha_1, \alpha_2, \ldots, \alpha_n)</math> and : <math>x^\alpha = x_1^{\alpha_1} x_2^{\alpha_2} \cdots x_n^{\alpha_n}.</math> We also use the notation : <math>D^\alpha = \frac{1}{i^{|\alpha|}} \partial_{x_1}^{\alpha_1}\partial_{x_2}^{\alpha_2} \cdots \partial_{x_n}^{\alpha_n}. </math> Then the operator ''P''(D) defined on the space of infinitely differentiable functions of compact support on '''R'''<sup>''n''</sup> by : <math> P(\operatorname{D}) \phi = \sum_\alpha c_\alpha \operatorname{D}^\alpha \phi</math> is essentially self-adjoint on ''L''<sup>2</sup>('''R'''<sup>''n''</sup>). {{math theorem|Let ''P'' a polynomial function on '''R'''<sup>''n''</sup> with real coefficients, '''F''' the Fourier transform considered as a unitary map ''L''<sup>2</sup>('''R'''<sup>''n''</sup>) β ''L''<sup>2</sup>('''R'''<sup>''n''</sup>). Then '''F'''*''P''(D)'''F''' is essentially self-adjoint and its unique self-adjoint extension is the operator of multiplication by the function ''P''.}} More generally, consider linear differential operators acting on infinitely differentiable complex-valued functions of compact support. If ''M'' is an open subset of '''R'''<sup>''n''</sup> : <math>P \phi(x) = \sum_\alpha a_\alpha (x) \left[D^\alpha \phi\right](x)</math> where ''a''<sub>Ξ±</sub> are (not necessarily constant) infinitely differentiable functions. ''P'' is a linear operator : <math> C_0^\infty(M) \to C_0^\infty(M).</math> Corresponding to ''P'' there is another differential operator, the '''[[formal adjoint]]''' of ''P'' : <math> P^\mathrm{*form} \phi = \sum_\alpha D^\alpha \left(\overline{a_\alpha} \phi\right)</math> {{math theorem|The adjoint ''P''* of ''P'' is a restriction of the distributional extension of the formal adjoint to an appropriate subspace of <math>L^2</math>. Specifically: <math display="block">\operatorname{dom} P^* = \left\{u \in L^2(M): P^{\mathrm{*form}}u \in L^2(M) \right\}.</math>}}
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