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Transposable element
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=== Specific applications === * TEs are also a widely used tool for mutagenesis of most experimentally tractable organisms. The Sleeping Beauty transposon system has been used extensively as an insertional tag for identifying cancer genes.<ref name=":1" /> * The Tc1/mariner-class of TEs Sleeping Beauty transposon system, awarded Molecule of the Year in 2009,<ref name="Wojciech Makałowski p. 337-359" /> is active in mammalian cells and is being investigated for use in human gene therapy.<ref name=":2" /><ref name=":3" /><ref name=":4" /> * TEs are used for the reconstruction of phylogenies by the means of presence/absence analyses.<ref name=":5" /> Transposons can act as biological mutagen in bacteria. * Common organisms which the use of Transposons has been well developed are: **''[[Drosophila]]''<ref>{{cite journal | vauthors = Tempel S, Rousseau C, Tahi F, Nicolas J | title = ModuleOrganizer: detecting modules in families of transposable elements | journal = BMC Bioinformatics | volume = 11 | pages = 474 | date = September 2010 | pmid = 20860790 | pmc = 2955051 | doi = 10.1186/1471-2105-11-474 | doi-access = free }}</ref> ** ''[[Arabidopsis thaliana]]''<ref name="Mobilization of transposons by a mu"/> ** ''[[Escherichia coli]]''
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