Editing Interactome (section)

===Predicted interactomes===
As described above, PPIs and thus whole interactomes can be predicted. While the reliability of these predictions is debatable, they are providing hypotheses that can be tested experimentally. Interactomes have been predicted for a number of species, e.g.
* Human (''[[Homo sapiens]]'')<ref name="pmid15657099">{{cite journal |vauthors=Brown KR, Jurisica I |title=Online predicted human interaction database |journal=Bioinformatics |volume=21 |issue=9 |pages=2076–82 |year=2005 |pmid=15657099 |doi=10.1093/bioinformatics/bti273 |doi-access=free }}</ref>
* Rice (''[[Oryza sativa]]'')<ref name="pmid21575196">{{cite journal |vauthors=Gu H, Zhu P, Jiao Y, Meng Y, Chen M |title=PRIN: a predicted rice interactome network |journal=BMC Bioinformatics |volume=12 |pages=161 |year=2011 |pmid=21575196 |pmc=3118165 |doi=10.1186/1471-2105-12-161 |doi-access=free }}</ref>
* ''[[Xanthomonas oryzae]]''<ref name="pmid24113387">{{cite journal |vauthors=Guo J, Li H, Chang JW, Lei Y, Li S, Chen LL |title=Prediction and characterization of protein–protein interaction network in Xanthomonas oryzae pv. oryzae PXO99 A |journal=Res. Microbiol. |volume=164 |issue=10 |pages=1035–44 |year=2013 |pmid=24113387 |doi=10.1016/j.resmic.2013.09.001 |doi-access=free }}</ref>
* ''[[Arabidopsis thaliana]]''<ref name="pmid17675552">{{cite journal |vauthors=Geisler-Lee J, O'Toole N, Ammar R, Provart NJ, Millar AH, Geisler M |title=A predicted interactome for Arabidopsis |journal=Plant Physiol. |volume=145 |issue=2 |pages=317–29 |year=2007 |pmid=17675552 |pmc=2048726 |doi=10.1104/pp.107.103465 }}</ref>
* Tomato (''[[Solanum lycopersicum]]'')<ref>{{Cite journal|last1=Yue|first1=Junyang|last2=Xu|first2=Wei|last3=Ban|first3=Rongjun|last4=Huang|first4=Shengxiong|last5=Miao|first5=Min|last6=Tang|first6=Xiaofeng|last7=Liu|first7=Guoqing|last8=Liu|first8=Yongsheng|date=2016-01-01|title=PTIR: Predicted Tomato Interactome Resource|journal=Scientific Reports|volume=6|pages=25047|doi=10.1038/srep25047|issn=2045-2322|pmid=27121261|pmc=4848565|bibcode=2016NatSR...625047Y}}</ref>
* Field mustard (''[[Brassica rapa]]'')<ref>{{Cite journal|last1=Yang|first1=Jianhua|last2=Osman|first2=Kim|last3=Iqbal|first3=Mudassar|last4=Stekel|first4=Dov J.|last5=Luo|first5=Zewei|last6=Armstrong|first6=Susan J.|last7=Franklin|first7=F. Chris H.|date=2012-01-01|title=Inferring the Brassica rapa Interactome Using Protein–Protein Interaction Data from Arabidopsis thaliana|journal=Frontiers in Plant Science|volume=3|pages=297|doi=10.3389/fpls.2012.00297|issn=1664-462X|pmc=3537189|pmid=23293649|doi-access=free}}</ref> 
* ''Maize, corn ([[Maize|Zea mays]])''<ref>{{Cite journal|last1=Zhu|first1=Guanghui|last2=Wu|first2=Aibo|last3=Xu|first3=Xin-Jian|last4=Xiao|first4=Pei-Pei|last5=Lu|first5=Le|last6=Liu|first6=Jingdong|last7=Cao|first7=Yongwei|last8=Chen|first8=Luonan|last9=Wu|first9=Jun|date=2016-02-01|title=PPIM: A Protein–Protein Interaction Database for Maize|journal=Plant Physiology|volume=170|issue=2|pages=618–626|doi=10.1104/pp.15.01821|issn=1532-2548|pmc=4734591|pmid=26620522}}</ref>
* Poplar (''[[Populus trichocarpa]]'')<ref>{{Cite journal|last1=Rodgers-Melnick|first1=Eli|last2=Culp|first2=Mark|last3=DiFazio|first3=Stephen P.|date=2013-01-01|title=Predicting whole genome protein interaction networks from primary sequence data in model and non-model organisms using ENTS|journal=BMC Genomics|volume=14|pages=608|doi=10.1186/1471-2164-14-608|issn=1471-2164|pmc=3848842|pmid=24015873 |doi-access=free }}</ref>
* ''[[SARS-CoV-2]]''<ref name="pmid32244779">{{cite journal |vauthors=Guzzi PH, Mercatelli D, Ceraolo C, Giorgi FM |title=Master Regulator Analysis of the SARS-CoV-2/Human Interactome |journal=Journal of Clinical Medicine |volume=9 |issue=4 |pages=982–988 |year=2020 |pmid=32244779 |doi=10.3390/jcm9040982 |pmc=7230814 |doi-access=free }}</ref>
[[File:Figure1 interactome highres.tif|thumb|Representation of the predicted SARS-CoV-2/Human interactome<ref name="pmid32244779"/>]]