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Coagulation
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====Plasmin==== [[Plasmin]] is generated by proteolytic cleavage of plasminogen, a plasma protein synthesized in the liver. This cleavage is catalyzed by [[tissue plasminogen activator]] (t-PA), which is synthesized and secreted by endothelium. Plasmin proteolytically cleaves fibrin into fibrin degradation products that inhibit excessive fibrin formation.{{citation needed|date=June 2022}}
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