Editing Frameshift mutation (section)

===Hypertrophic cardiomyopathy===

[[Hypertrophic cardiomyopathy]] is the most common cause of [[sudden cardiac death|sudden death]] in young people, including trained athletes, and is caused by mutations in genes encoding proteins of the cardiac sarcomere. Mutations in the Troponin C gene (''[[TNNC1]]'') are a rare genetic cause of hypertrophic cardiomyopathy. A recent study has indicated that a frameshift mutation (c.363dupG or p.Gln122AlafsX30) in Troponin C was the cause of hypertrophic cardiomyopathy (and sudden cardiac death) in a 19-year-old male.<ref name="pmid21262074">{{cite journal |vauthors=Chung WK, Kitner C, Maron BJ |title=Novel frameshift mutation in Troponin C ( TNNC1) associated with hypertrophic cardiomyopathy and sudden death |journal=Cardiol Young |volume=21 |issue=3 |pages=345–8 |date=June 2011 |pmid=21262074 |doi=10.1017/S1047951110001927 |s2cid=46682245 }}</ref>