Editing Platelet (section)

===Adaptive immunity===
Activated platelets are able to participate in [[adaptive immunity]], interacting with [[antibody|antibodies]]. They are able to specifically bind [[immunoglobulin G|IgG]] through [[FcγRIIA]], a receptor for IgG's constant fragment (Fc). When activated and bound to IgG-[[opsonin|opsonised]] bacteria, platelets release reactive oxygen species (ROS), antimicrobial peptides, [[defensins]], kinocidins and [[proteases]], killing the bacteria directly.<ref name=":2">{{cite journal |vauthors=Palankar R, Kohler TP, Krauel K, Wesche J, Hammerschmidt S, Greinacher A |title=Platelets kill bacteria by bridging innate and adaptive immunity via platelet factor 4 and FcγRIIA |journal=Journal of Thrombosis and Haemostasis |volume=16 |issue=6 |pages=1187–97 |date=June 2018 |pmid=29350833 |doi=10.1111/jth.13955 |doi-access=free}}</ref> Platelets also secrete proinflammatory and procoagulant mediators such as inorganic [[polyphosphates]] or [[platelet factor 4]] (PF4), connecting innate and adaptive immune responses.<ref name=":2"/><ref>{{cite journal |vauthors=McMorran BJ, Wieczorski L, Drysdale KE, Chan JA, Huang HM, Smith C, Mitiku C, Beeson JG, Burgio G, Foote SJ |title=Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum |journal=Science |volume=338 |issue=6112 |pages=1348–51 |date=December 2012 |pmid=23224555 |doi=10.1126/science.1228892 |bibcode=2012Sci...338.1348M |s2cid=206544569 |url=https://zenodo.org/record/261563}}</ref>