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Androgen
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=== Female ovarian and adrenal androgens === The ovaries and adrenal glands also produce androgens, but at much lower levels than the testes. Regarding the relative contributions of ovaries and adrenal glands to female androgen levels, in a study with six menstruating women the following observations have been made:<ref name="1974 Abraham Ovarian Adrenal Androgens">{{cite journal | vauthors = Abraham GE | title = Ovarian and adrenal contribution to peripheral androgens during the menstrual cycle | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 39 | issue = 2 | pages = 340β346 | date = August 1974 | pmid = 4278727 | doi = 10.1210/jcem-39-2-340 }}</ref> * Adrenal contribution to peripheral T, DHT, A, DHEA and DHEA-S is relatively constant throughout the [[menstrual cycle]]. * Ovarian contribution of peripheral T, A and DHEA-S reaches maximum levels at mid-cycle, whereas ovarian contribution to peripheral DHT and DHEA does not seem to be influenced by the menstrual cycle. * Ovary and adrenal cortex contribute equally to peripheral T, DHT and A, with the exception that at mid-cycle ovarian contribution of peripheral A is twice that of the adrenal. * Peripheral DHEA and DHEA-S are produced mainly in the adrenal cortex which provides 80% of DHEA and over 90% of DHEA-S. {| class="wikitable" |+ Ovarian and adrenal contribution to peripheral androgens during the menstrual cycle<ref name="1974 Abraham Ovarian Adrenal Androgens"/> ! Androgen || '''Ovarian (%) (F, M, L)''' || '''Adrenal (%)''' |- | DHEA || 20 || 80 |- | DHEA-S || 4, 10, 4 || 90β96 |- | Androstenedione || 45, 70, 60 || 30β55 |- | Testosterone || 33, 60, 33 || 40β66 |- | DHT || 50 || 50 |- | colspan="3" | F = early follicular, M = midcycle, L = late luteal phase. |}
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