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Auditory cortex
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===Development=== Like many areas in the neocortex, the functional properties of the adult primary auditory cortex (A1) are highly dependent on the sounds encountered early in life. This has been best studied using animal models, especially cats and rats. In the rat, exposure to a single frequency during postnatal day (P) 11 to 13 can cause a 2-fold expansion in the representation of that frequency in A1.<ref>{{cite journal|last=de Villers-Sidani|first=Etienne|author2=EF Chang |author3=S Bao |author4=MM Merzenich |title=Critical period window for spectral tuning defined in the primary auditory cortex (A1) in the rat|journal=J Neurosci|volume=27|issue=1|pages=180β9|doi=10.1523/JNEUROSCI.3227-06.2007|year=2007|pmid=17202485|pmc=6672294|url=https://cloudfront.escholarship.org/dist/prd/content/qt20p2h3wt/qt20p2h3wt.pdf}}</ref> Importantly, the change is persistent, in that it lasts throughout the animal's life, and specific, in that the same exposure outside of that period causes no lasting change in the tonotopy of A1. Sexual dimorphism within the auditory cortex can be seen in humans between males in females through the planum temporale, encompassing Wernicke's region, for the planum temporale within males has been observed to have a larger planum temporale volume on average, reflecting previous studies discussing interactions between sex hormones and asymmetrical brain development.<ref>{{Cite journal|last1=Kulynych|first1=J. J.|last2=Vladar|first2=K.|last3=Jones|first3=D. W.|last4=Weinberger|first4=D. R.|date=March 1994|title=Gender differences in the normal lateralization of the supratemporal cortex: MRI surface-rendering morphometry of Heschl's gyrus and the planum temporale|journal=Cerebral Cortex |volume=4|issue=2|pages=107β118|doi=10.1093/cercor/4.2.107|issn=1047-3211|pmid=8038562}}</ref>
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