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== Use in research == Adami and Ofria, in collaboration with others, have used Avida to conduct research in digital evolution, and the scientific journals ''[[Nature (journal)|Nature]]'' and ''[[Science (journal)|Science]]'' have published four of their papers. The 2003 paper "The Evolutionary Origin of Complex Features" describes the evolution of a mathematical [[Equality (mathematics)|equal]]s [[operator (programming)|operation]] from simpler bitwise operations.<ref>{{cite journal|last1=Lenski|first1=R. E.|last2=Ofria|first2=C.|last3=Pennock|first3=R. T.|last4=Adami|first4=C.|date=2003|author1-link=Richard Lenski|author2-link=Charles Ofria|author3-link=Robert T. Pennock|author4-link=Chris Adami|title=The evolutionary origin of complex features|journal=Nature|volume=423|pages=139β144|url=http://myxo.css.msu.edu/papers/nature2003/Nature03_Complex.pdf|doi=10.1038/nature01568|pmid=12736677|issue=6936|bibcode=2003Natur.423..139L|s2cid=4401833|access-date=2012-01-30|archive-date=2021-01-21|archive-url=https://web.archive.org/web/20210121232710/http://myxo.css.msu.edu/papers/nature2003/Nature03_Complex.pdf|url-status=dead}}</ref>
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