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Calcium channel blocker
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=== Dihydropyridine === [[File:Dipines.svg|thumb|right|class=skin-invert-image|General chemical structure of dihydropyridine calcium channel blockers (dipines)]] Dihydropyridine (DHP) calcium channel blockers are derived from the molecule [[dihydropyridine]] and often used to reduce systemic vascular resistance and arterial pressure. Sometimes when they are used to treat [[angina pectoris|angina]], the vasodilation and hypotension can lead to reflex [[tachycardia]], which can be detrimental for patients with [[ischemic]] symptoms because of the resulting increase in [[myocardial]] oxygen demand. Dihydropyridine calcium channel blockers can worsen [[proteinuria]] in patients with [[nephropathy]].<ref>{{Cite journal |vauthors=Remuzzi G, Scheppati A, Ruggenenti P |year=2002 |title=Clinical Practice. Nephropathy in Patients with Type 2 Diabetes |journal=New England Journal of Medicine |volume=346 |issue=15 |pages=1145β51 |doi=10.1056/NEJMcp011773 |pmid=11948275}}</ref> This CCB class is easily identified by the suffix "-dipine". * [[Amlodipine]] (Norvasc) * [[Aranidipine]] (Sapresta) * [[Azelnidipine]] (Calblock) * [[Barnidipine]] (HypoCa) * [[Benidipine]] (Coniel) * [[Cilnidipine]] (Atelec, Cinalong, Siscard) Not available in US * [[Clevidipine]] (Cleviprex) * [[Efonidipine]] (Landel) * [[Felodipine]] (Plendil) * [[Isradipine]] (DynaCirc, Prescal) * [[Lacidipine]] (Motens, Lacipil) * [[Lercanidipine]] (Zanidip) * [[Manidipine]] (Calslot, Madipine) * [[Nicardipine]] (Cardene, Carden SR) * [[Nifedipine]] (Procardia, Adalat) * [[Nilvadipine]] (Nivadil) * [[Nimodipine]] (Nimotop) This substance can pass the [[Blood brain barrier|blood-brain barrier]] and is used to prevent [[cerebral vasospasm]]. * [[Nisoldipine]] (Baymycard, Sular, Syscor) * [[Nitrendipine]] (Cardif, Nitrepin, Baylotensin) * [[Pranidipine]] (Acalas)
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