Editing Carbamoyl phosphate (section)

==Production==
It is produced from [[bicarbonate]], [[ammonia]] (derived from [[amino acids]]), and [[phosphate]] (from [[Adenosine triphosphate|ATP]]).<ref name=":0">{{cite book | vauthors = Bhagavan NV, Ha CE |chapter=Protein and Amino Acid Metabolism |date=2015 |title=Essentials of Medical Biochemistry |edition=Second |pages=227–268| veditors = Bhagavan NV, Ha CE|location=San Diego|publisher=Academic Press|language=en|doi=10.1016/b978-0-12-416687-5.00015-4|isbn=978-0-12-416687-5 }}</ref> The synthesis is catalyzed by the enzyme [[carbamoyl phosphate synthetase]].<ref name=":0" /> This uses three reactions as follows:

* {{chem|HCO|3|−}} + ATP → ADP + {{chem|HO–C(O)–OPO|3|2−}} (carboxyl phosphate)
* {{chem|HO–C(O)–OPO|3|2−}}  +  NH<sub>3</sub>  + OH<sup>−</sup>   →  {{chem|HPO|4|2−}}  +  [[Carbamate|<sup>−</sup>O–C(O)NH<sub>2</sub>]]  +  H<sub>2</sub>O
*<sup>−</sup>O–C(O)NH<sub>2</sub>  +  ATP  →  ADP +  {{chem|H|2|NC(O)OPO|3|2−}}